A physician, historian, linguist, ethnologist and naturalist, he was born in El Tocuyo, on September 19, 1958, and passed away in Valencia, on April 10, 1929. He was a member of the Venezuelan National Academy of Medicine, Language and History. He was Lisandro Alvarado.

He attended the La Concordia School, founded by his godfather Egidio Montesinos at El Tocuyo. He later moved to Trujillo, where in 1871, he was awarded a High-School Diploma of Philosophy by the National Male School.

In 1878, he went to Caracas to enter the Central University of Venezuela (UCV). There, he studied Roman and Canonic Law, mineralogy, higher calculation and medicine. Afterwards, he registered in the Military Academy of Mathematics. In 1984, he got the Bachelor's Degree of Medical Sciences and also, that same year, the Doctor of Medicine Degree with the thesis entitled: "Thermometry is one of the breakthroughs of pathology" and "Diagnosis of inguinal hernia." In 1888, he was entrusted with the Rural First Aid Post in Guanare, Portuguesa state. Later on, he was commissioned to El Tinaco, during the epidemic that year.

He was appointed president of the National School at Guanare. In 1880, Alvarado was appointed Consul in Southampton, U.K. He returned in 1981 and voiced acknowledgment of the positivist doctrine. In 1893, he was co-founder of the Caracas Athenaeum and deputy at the Zamora State Constituent Assembly. In 1900, he released his "Remarks on the 1810 Revolution," "Political crimes in the Venezuelan History," and "Insight." At this stage, he published several case studies, namely: "Neurosis of Venezuelan renowned men," "About the country civil wars," "Evolution of the Spanish language in Venezuela," "Glossary of Venezuelan indigenous terms," "Phonetic alterations of the Spanish language in Venezuela," and "Glossary of the colloquial Spanish language in Venezuela." In 1907, he released his "Comments on Gil Fortoul's Constitutional History of Venezuela."

His remains rest at the National Pantheon since 1980. As a tribute, the Barquisimeto Experimental Higher Studies Center was renamed after him as Lisandro Alvarado Central-Western University. Also, the renowned high-school bears his name.